| Activité scientifique |
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Mon activité de recherche, depuis 2000 (année de mon D.E.A.), est essentiellement consacrée aux effets d’une activité physique sur la santé cardio-respiratoire.
Elle s’articule autour de deux axes :
– Les bénéfices de l’activité physique à la santé chez des patients atteints de pathologies respiratoires
– Les effets délétères possibles de l’activité physique intense chez des sportifs de haut-niveau
La pratique régulière d’une activité physique a des bienfaits sur la santé cardio-respiratoire des patients atteints de pathologies respiratoires, mais à l’opposé une activité physique trop intense peut être responsable du développement de problèmes cardio-respiratoires chez des sportifs élite. Mes recherches actuelles sont axées sur la compréhension des mécanismes de développement de pathologies essentiellement respiratoires chez les athlètes élite en lien avec la pollution.
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| Scientifical activity |
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My research activity is devoted mainly to the effects of physical activity on cardiorespiratory health, and especially:
1. The benefits of physical activity to health in patients with respiratory diseases
2. The possible deleterious effects of intense training in elite athletes’ airways.
Regular physical activity has beneficial effects on cardiorespiratory health of patients with respiratory diseases, but to the opposite intense training may be responsible for respiratory disorder development in elite athletes. My current research focuses primarily on the understanding of mechanisms implied in the development of respiratory disease in elite athletes, in relation to the environment, and especially chlorine byproducts in elite swimmers.<!– [if gte mso 9]>–>
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| Publication(s) |
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27. Combes A, Dekerle J, Webborn N, Watt P, <b>Bougault V</b>, Daussin FN. <a href="http://www.ncbi.nlm.nih.gov/pubmed/26359238" rel="nofollow">Exercise-induced metabolic fluctuations influence AMPK, p38-MAPK and CaMKII phosphorylation in human skeletal muscle.</a> Physiol Rep 2015;3(9). pii: e12462.
<b> </b>26. Morissette MC, Murray N, Turmel J, Milot J, Boulet LP, <b>Bougault V</b>. <a href="http://www.ncbi.nlm.nih.gov/pubmed/26279287" rel="nofollow">Increased exhaled breath condensate 8-isoprostane after a swimming session in competitive swimmers.</a> Eur J Sport Sci 2015
25. Mountjoy M, Fitch K, Boulet LP, <b>Bougault V</b>, van Mechelen W, Verhagen E. <a href="http://www.ncbi.nlm.nih.gov/pubmed/25819982" rel="nofollow">Prevalence and characteristics of asthma in the aquatic disciplines.</a> J Allergy Clin Immunol 2015 ;136(3) :588-94
24. Rundell KW, Anderson SD, Sue-Chu M, <b>Bougault V</b>, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/25880506" rel="nofollow">Air quality and temperature effects on exercise-induced bronchoconstriction.</a> Compr Physiol 2015 ; 1;5(2):579-610
<b> </b>23.<b> Bougault V</b>, Blouin E, Turmel J, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/25789614" rel="nofollow">Airway response to methacholine following eucapnic voluntary hyperpnea in athletes.</a> PLoS One 2015 ;10(3):e0121781
22. Laviolette L, Laveneziana P; <b>ERS Research Seminar Faculty</b>. <a href="http://www.ncbi.nlm.nih.gov/pubmed/24525437" rel="nofollow">Dyspnoea: a multidimensional and multidisciplinary approach.</a> Eur Respir J. 2014;43(6):1750-62
21. Couillard S, <b>Bougault V</b>, Turmel J, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/24264387" rel="nofollow">Perception of bronchoconstriction following methacholine and eucapnic voluntary hyperpnea challenges in elite athletes.</a> Chest. 2014;145(4):794-802
20. Hallstrand TS, Kippelen P, Larsson J, <b>Bougault V</b>, van Leeuwen JC, Driessen JM, Brannan JD. <a href="http://www.ncbi.nlm.nih.gov/pubmed/23830134" rel="nofollow">Where to from here for exercise-induced bronchoconstriction: the unanswered questions.</a> Immunol Allergy Clin North Am 2013;33(3):423-42
19.<b> Bougault V</b>, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/23830132" rel="nofollow">Airways disorders and the swimming pool.</a> Immunol Allergy Clin North Am 2013;33(3):395-408
18. Oussaidene K, Prieur F, <b>Boug</b><b>ault V</b>, Borel B, Matran R, Mucci P. <a href="http://www.ncbi.nlm.nih.gov/pubmed/23579360" rel="nofollow">Cerebral oxygenation during hyperoxia-induced increase in exercise tolerance for untrained men.</a> Eur J Appl Physiol 2013;113(8):2047-56
17. Turmel J, Poirier P, <b>Bougault V</b>, Blouin E, Belzile M, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/23528622" rel="nofollow">Cardiorespiratory screening in elite endurance sports athletes: the Quebec study.</a> Phys Sportsmed 2012;40(3):55-65<b></b>
<b> </b>16.<b> Bougault V</b>, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/23134238" rel="nofollow">Is there a potential link between indoor chlorinated pool environment and airway remodeling/inflammation in swimmers?</a> Expert Rev Respir Med 2012;6(5):469-71<b></b>
<b> </b>15. Turmel J, <b>Bougault V</b>, Boulet LP, Poirier P. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22828668" rel="nofollow">Exaggerated blood pressure response to exercise in athletes: dysmetabolism or altered autonomic nervous system modulation?</a> Blood Press Monit 2012;17(5):184-92
14. Kippelen P, Fitch KD, Anderson SD, <b>Bougault V</b>, Boulet LP, Rundell KW, Sue-Chu M, McKenzie DC. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22522585" rel="nofollow">Respiratory health of elite athletes – preventing airway injury: a critical review.</a> Br J Sports Med 2012;46(7):471-6
13. Turmel J, <b>Bougault V</b>, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22449054" rel="nofollow">Seasonal variations of cough reflex sensitivity in elite athletes training in cold air environment.</a> Cough 2012 ;26;8(1):2<b></b>
<b> </b>12.<b> Bougault V</b>, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22247299" rel="nofollow">Airway dysfunction in swimmers.</a> Br J Sports Med 2012;46(6):402-6
<b> </b>11.<b> Bougault V</b>, Loubaki L, Joubert P, Turmel J, Couture C, Laviolette M, Chakir J, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22196771" rel="nofollow">Airway remodeling and inflammation in competitive swimmers training in indoor chlorinated swimming pools.</a> J Allergy Clin Immunol 2012;129(2):351-8
10.<b> Bougault V</b>, Turmel J, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/21167573" rel="nofollow">Airway hyperresponsiveness in elite swimmers: is it a transient phenomenon?</a> J Allergy Clin Immunol 2011;127(4):892-8<b></b>
<b> </b>9.<b> Bougault V</b>, Turmel J, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/20545706" rel="nofollow">Effect of intense swimming training on rhinitis in high-level competitive swimmers.</a> Clin Exp Allergy 2010;40(8):1238-46
8.<b> Bougault V</b>, Turmel J, Boulet LP. <a href="http://www.ncbi.nlm.nih.gov/pubmed/20363843" rel="nofollow">Bronchial challenges and respiratory symptoms in elite swimmers and winter sport athletes: Airway hyperresponsiveness in asthma: its measurement and clinical significance.</a> Chest 2010;138(2 Suppl):31S-37S
<b> </b>7.<b> Bougault V</b>, Turmel J, St Laurent J, Bertrand M, Boulet LP. Asthma, airway inflammation and epithelial damage in swimmers and cold-air athletes. Eur Respir J 2009;33:740-6
6.<b> Bougault V</b>, Turmel J, Levesque B, Boulet LP. Respiratory health of swimmers: a review. Sports Med 2009;39(4):295-312
5. Rowland T, <b>Bougault V</b>, Walther G, Nottin S, Vinet A, Obert P. Cardiac responses to swim bench exercise in age-group swimmers and non-athletic children. J Sci Med Sport 2008; 12(2):266-72
4.<b> Bougault V, </b>Nottin S, Doucende G, Obert P.<b> </b>Reproducibility of left ventricular Tissue Doppler Imaging during exercise. Int J Sports Med 2008;29:395-400
3.<b> Bougault V</b>, Lonsdorfer-Wolf E, Charloux A, Richard R, Geny B, Oswald-Mammosser M. Does thoracic bioimpedance accurately determine cardiac output in chronic obstructive pulmonary disease patients during maximal or intermittent exercise ? Chest 2005 ; 127 : 1122-31
2. Lonsdorfer-Wolf E, <b>Bougault V</b>, Doutreleau S, Lonsdorfer J, Oswald-Mammosser M. Intermittent exercise test in COPD patients : how do the pulmonary hemodynamic adapt ? Med Sci Sports Exerc 2004 ; 36 (12) : 2032-9
1.<b> Bougault V</b>, Rasseneur L, Doutreleau S, Oswald-Mammosser M. Intérêts d’une activité physique en piscine chez l’asthmatique ? Science et Sports 2005 ; 20 : 1-11
CHAPITRES DE LIVRES
3. <b>Bougault V</b>. L’asthmatique doit-il faire du sport et le sport forme-t-il des asthmatiques ? In le sport est-il un médicament ?, André Thévenon. 2015 ; editions Sauramps Medical : 44-55
2. Fabre C, Borel B, <b>Bougault V</b>. Les maladies respiratoires. In L’enfant et l’activité physique : de la théorie à la pratique, Ratel S et Martin V. 2014 ; Editions Désiris. Mondovi :341-364
1.<b> Bougault V</b>, Oswald-Mammosser M, Lonsdorfer J. Réentraînement à l’effort dans l’asthme. In Les allergies, les comprendre et les prévenir, De Blay F, Grimfeld A et Just J. 2004 ; Expansion Scientifique Française. Paris : 110-117
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